Fasting Hyperglycemia Predicts the Magnitude of Postprandial Hyperglycemia

Autor: Ahmad Izard, Mary F. Carroll, Katrina Riboni, David S. Schade, Mark R. Burge
Rok vydání: 2002
Předmět:
Zdroj: Diabetes Care. 25:1247-1248
ISSN: 1935-5548
0149-5992
Popis: Postprandial blood glucose is a strong predictor of HbA1c levels and cardiovascular mortality (1–3). The treatment of postprandial hyperglycemia has become prominent with the recent availability of oral hypoglycemic agents that specifically target the postmeal glucose rise. The aim of this study was to examine the relationship between the fasting blood glucose level and the magnitude of the postprandial glucose rise in type 2 diabetes. Specifically, if the fasting blood glucose level is a determinant of the postprandial glucose excursion, then correction of fasting hyperglycemia should precede attempts at limiting postprandial hyperglycemia. All results are expressed as means ± SD. A total of 21 subjects (11 men and 10 women) with non-insulin-requiring type 2 diabetes and average glycemic control (HbA1c 7.3 ± 1.4%) were recruited. The subjects were aged 59.4 ± 11.1 years, were moderately obese (BMI 31.3 ± 5.5 kg/m2), and had been diagnosed with diabetes for 8.7 ± 8.8 years. Two of the patients were treated with diet and exercise alone, and the remaining 19 were taking one or two oral hypoglycemic agents for diabetes control ( n = 13 for sulfonylureas, n = 6 for …
Databáze: OpenAIRE