| Autor: |
Hong Hao Le Thi, Truong Nguyen Xuan, To Quynh Cung Thi, Thao Dang Phuong, Tien Bui Cao, Son Tran Cao |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Heavy metals and arsenic concentrations in water, agricultural soil, and rice in Ngan Son district, Bac Kan province, Vietnam. 2:24-31 |
| ISSN: |
2615-9252 |
| DOI: |
10.47866/2615-9252/vjfc.58 |
| Popis: |
A simple and accurate method has been developed for the simultaneous determination of fourpyrrolizidine alkaloids (PAs) including echimidine, senecionine, jacobine and intermidine in foodsupplements of plant origin. The instrumental conditions including the use of TSK-Gel columnfor the separation and an MS/MS detector in positive ESI source, multi-reactive monitoring(MRM) mode for quantitation were optimized. The method has fully validated and meets theperformance requirement of AOAC with good specificity. The linearity varies from 1.0 µg/kg to40 µg/kg, the LOD was of 0.3 µg/kg; the repeatability and recovery range from 3.6% to 7.5% and88.7% to 117%, respectively. The method was applied to determine PAs in 90 food supplementsamples, of which 26 samples (28.8%) contain PAs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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