Design, synthesis and evaluation of the anti-breast cancer activity of 1,3-oxazolo[4,5-d]pyrimidine and 1,3-oxazolo[5,4-d]pyrimidine derivatives

Autor: Yevheniia Velihina, Raey Gesese, Victor Zhirnov, Oleksandr Kobzar, Benjamin Bui, Stepan Pilyo, Andriy Vovk, Hai-Ying Shen, Volodymyr Brovarets
Rok vydání: 2023
Předmět:
Zdroj: RSC Medicinal Chemistry. 14:692-699
ISSN: 2632-8682
DOI: 10.1039/d2md00377e
Popis: The prepared oxazolopyrimidine derivatives exhibited high anti-breast-cancer activity and ADK suppression, indicating their potential as candidates in the targeted search for new, highly effective antitumor drugs.
Databáze: OpenAIRE