p53 protein expression as prognostic factor in patients undergoing radical prostatectomy for prostatic cancer

Autor:	Roberto Tarabuzzi, G. Fasolis, S. Cappia, Ivano Morra, E. Leonardo, M. Mari, Francesco Porpiglia, A. Rocca, Dario Fontana
Rok vydání:	1996
Předmět:	Oncology medicine.medical_specialty Prognostic factor business.industry Prostatectomy medicine.medical_treatment Cancer General Medicine medicine.disease Internal medicine P53 protein Medicine In patient business
Zdroj:	Urologia Journal. 63:21-24
ISSN:	1724-6075 0391-5603
DOI:	10.1177/039156039606301s04
Popis:	The authors give preliminary data on the evaluation of the p53 protein expression as prognostic factor in patients subjected to radical prostatectomy for prostatic cancer. p53 protein immunohistochemical nuclear staining was carried out on neoplastic tissue obtained from systematic sextant prostatic biopsies at the time of diagnosis. Out of 46 Patients 15 (32%) were p53 positive (p53+). No statistical correlation was observed between P53 staining, preoperative PSA and pathological Gleason Score, while the rate of patients with nodal involvement (pN+) was higher in the p53+ group than the P53- group with low statistical significance (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8ce0204b568cbbb41a19185b66a49946 https://doi.org/10.1177/039156039606301s04 Zobrazit plný text záznamu