Is Fibrinogen an Effective Marker for Predicting Mortality in Patients with Gastric Cancer?

Autor: Erdinç Çetinkaya, Özgür Akgül, Hikmet Pehlevan Özel, Tolga Dinç
Rok vydání: 2021
Předmět:
Zdroj: Indian Journal of Surgery. 83:761-767
ISSN: 0973-9793
0972-2068
DOI: 10.1007/s12262-021-02915-x
Popis: We aimed to determine the parameters that affect the mortality of patients operated on for gastric cancer and to investigate whether fibrinogen affects mortality or not. This retrospective clinical study included patients who underwent surgery due to gastric adenocarcinoma between January 2011 and January 2014. Patients’ demographic data, laboratory values, (hemogram parameters, fibrinogen, albumin, and tumor markers), operations, lymph node dissections, parameters of histopathology reports, stages, mortality/survival status, metastasis status at follow-up, and admission/operation/follow-up were obtained from the hospital automation system and recorded using the statistical software. Patients were divided into two groups: deceased and survivors. Analyses were carried out to determine whether the parameters of the patients, including fibrinogen, affected survival. A total of 130 patients were included in the study. Of the patients, 91 were men and 39 were women. The mean age of the patients was 63.99 SD 11.22 years. The results of the analysis of the patients’ parameters revealed that the presence of lymphatic invasion, lymph node positivity, high metastatic lymph node ratio, and advanced stage were statistically significantly correlated with low survival (p
Databáze: OpenAIRE
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