Synthesis of d-fructopyranosides with 2-O-acyl-β-d-fructopyranosides

Autor:	Qiulong Xu, Feng Lin, Rui Lu, Liqun Yue
Rok vydání:	2014
Předmět:	Glycosylation Stereochemistry Organic Chemistry Ketose Ring (chemistry) Biochemistry Acceptor chemistry.chemical_compound chemistry Acetylation Drug Discovery lipids (amino acids peptides and proteins) Glycosyl Glycosyl donor
Zdroj:	Tetrahedron Letters. 55:98-100
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2013.10.128
Popis:	Glycosylation of 2-O-acyl fructopyranosides was investigated, which were shown to be effective glycosyl donors for d -fructopyranoside synthesis with good β-selectivity and yields. For bulky acceptor 4e, α-anomer 5e was obtained with α/β = 65:23. Unexpected ring-opening was observed during acetylation of 9, indicating the sensitivity of the fructopyranosyl ring.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8cc9a62eaa17bcb7988254b74e95b775 https://doi.org/10.1016/j.tetlet.2013.10.128 Zobrazit plný text záznamu Full Text from ScienceDirect