Study of the indices of antioxidant defense in mental maladaptation
| Autor: | L. A. Levchuk, E. V. Gutkevich, Ludmila P. Smirnova, V. Ya. Semke, Svetlana A. Ivanova, N. M. Krotenko |
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| Rok vydání: | 2012 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Antioxidant biology Physiology Glutathione peroxidase medicine.medical_treatment Glutathione reductase Malondialdehyde Lipid peroxidation chemistry.chemical_compound Endocrinology Blood serum chemistry Catalase Physiology (medical) Internal medicine Immunology medicine biology.protein Maladaptation |
| Zdroj: | Human Physiology. 38:543-547 |
| ISSN: | 1608-3164 0362-1197 |
| DOI: | 10.1134/s0362119712040135 |
| Popis: | Changes in the balance of the pro- and antioxidant systems were studied in patients with mental maladaptation induced by emotional stress. We found activation of lipid peroxidation associated with accumulation of malondialdehyde in erythrocytes and blood serum of the subjects. The activity of catalase and glutathione peroxidase in erythrocytes in patients with mental stress increased, whereas the activities of glutathione reductase, glutathione-S-transferase, and glucose-6-phosphate dehydrogenase significantly decreased as compared to the group of healthy individuals. Comparative chemiluminescent analysis of the blood serum revealed a decrease in general antioxidant properties of the blood in the groups studied after mental stress. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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