Atopic dermatitis in preschool children: prevalence, clinical and allergic characteristics and risk factors

Autor:	U F Lobanov, N V Shakhova, T S Ardatova, E M Kamaltynova
Rok vydání:	2018
Předmět:	Vitamin Anamnesis medicine.medical_specialty Pediatrics Passive smoking business.industry First year of life General Medicine Atopic dermatitis medicine.disease medicine.disease_cause chemistry.chemical_compound chemistry Epidemiology medicine Allergists Family history business
Zdroj:	Russian Journal of Allergy. 15:55-62
ISSN:	2686-682X 1810-8830
DOI:	10.36691/rja189
Popis:	Background. Information on atopic dermatitis (AD) epidemiology in preschool children is scarce. Objectives. To estimate the prevalence, clinical, allergological characteristics and risk factors of AD in preschool children. Materials and methods. 5156 children aged 3-6 years old living in the Altai Territory participated in the study. The study included a screening and clinical phases. At the screening stage of the study the prevalence of AD was evaluated using the Russian version of the ISAAC questionnaire, risk factors were evaluated using the additional questionnaire. At the clinical stage diagnosis of AD was verified by allergists. Results. The prevalence of atopic dermatitis was 9,9%. 73,8% of children had mild AD; 58,5% of children were sensitized: 25 (15,6%) to food allergens - 12 (7,2%) to egg, 12 (7,2%) to cow’s milk, 6 (3,6%) to wheat flour and 8 (4,9%) to fish. The most important inhaled allergens were house dust mites, the sensitivity to them was diagnosed in 44 (26,8%) children. The family anamnesis of allergic diseases increases risk of development of AD by 5 times (OR=5,7; 95% CI=4,1-7,9; p
Databáze:	OpenAIRE
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