Cell-free conversion of 1-deoxy-D-xylulose 5-phosphate and 2-C-methyl-D-erythritol 4-phosphate into β-carotene in higher plants and its inhibition by fosmidomycin

Autor:	Ulrich H. Maier, Klaus Kis, Adelbert Bacher, Meinhart H. Zenk, Monika Fellermeier, Silvia Sagner
Rok vydání:	1999
Předmět:	2-C-methyl-D-erythritol-4-phosphate Stereochemistry medicine.medical_treatment fungi Organic Chemistry Carotene Cell free Biochemistry Terpenoid Fosmidomycin Chloroplast chemistry.chemical_compound 1-deoxy-D-xylulose 5-phosphate Geranylgeraniol chemistry Drug Discovery medicine medicine.drug
Zdroj:	Tetrahedron Letters. 40:2743-2746
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(99)00361-5
Popis:	The presence of the deoxyxylulose pathway in chromo- and chloroplasts of various higher plants was demonstrated by the conversion of labelled 1-deoxy-D-xylulose 5-phosphate into β-carotene and geranylgeraniol, in the presence of ATP. The antibiotic fosmidomycin inhibited the formation of terpenoids from 1-deoxy-D-xylulose 5-phosphate, whereas it did not affect the conversion of 2- C -methyl-D-erythritol 4-phosphate or isopentenyl diphosphate into terpenoids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8ca068cd19dbb561f36692c951af7080 https://doi.org/10.1016/s0040-4039(99)00361-5 Zobrazit plný text záznamu Full Text from ScienceDirect