Search for Materials that Influence Human Medullary Thyroid Carcinoma Cell Proliferation
| Autor: | Hye Won Jang, Ji Young Park, Kwang Won Kim, Ji In Lee, Myung-Shik Lee, Hyun Won Shin, Moon Kyu Lee, Yong Ki Min, Sun Wook Kim, Keun Sook Kim, Jae Hoon Chung |
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| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases Medullary cavity business.industry Cell growth Thyroid Calcitonin secretion Thyroid carcinoma Endocrinology Somatostatin medicine.anatomical_structure Calcitonin Internal medicine medicine Cancer research business hormones hormone substitutes and hormone antagonists Gastrin |
| Zdroj: | Journal of Korean Endocrine Society. 24:93 |
| ISSN: | 1015-6380 |
| DOI: | 10.3803/jkes.2009.24.2.93 |
| Popis: | 1 , ABSTRACT Background: Surgical excision is the only effective treatment of medullary thyroid carcinoma (MTC) and there is no certain treatment for recurrence or distant metastasis. Materials that influence MTC cell proliferation were recently reported. Presently, we evaluated the influence of dexamethasone, somatostatin, progesterone, estradiol-17-beta, forskolin and gastrin on MTC cell proliferation and calcitonin secretion. Methods: Genomic DNA was extracted and sequenced from untreated thyroid TT cells and cells treated with 10 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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