Curcumin Topical Application For Symptomatic Treatment of Oral Lichen Planus: A Systematic Review of Evidence
| Autor: | Gihane Gharib Madkour, Sandy Shaaban Hassan, Amal A. Hussine |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Erythema business.industry Symptomatic treatment 030206 dentistry medicine.disease Pain alleviation Dermatology Clinical trial stomatognathic diseases 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Topical Curcumin Curcumin Medicine Oral lichen planus medicine.symptom business Adverse effect |
| Zdroj: | Egyptian Dental Journal. 65:1329-1339 |
| ISSN: | 2090-2360 |
| DOI: | 10.21608/edj.2019.72557 |
| Popis: | Objective: The aim of this systematic review was to assess the clinical effectiveness of topical curcumin, compared to topical corticosteroids for the management of symptomatic oral lichen planus.Material & Methods: Three databases were searched including MEDLINE-PubMed, Cochrane-Central & LILACS as well as Grey literature & hand-searching till September 2018. Randomized and non-randomized controlled clinical trials relevant to our topic were comprised.Results: Four studies met our eligibility criteria and were included in this systematic review; 2 randomized and 2 non-randomized controlled trials. All included studies reported clinical improvement of oral lichen planus, in terms of pain alleviation as well as reduction in erythema and ulceration, with the topical use of curcumin. No statistical significant differences were found when comparing the effectiveness of topical curcumin to topical corticosteroids. Conclusion: Topical curcumin application shows promising effects, comparable to topical corticosteroids for the symptomatic treatment of OLP, with no adverse effects. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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