Eco-Friendly and Facile Approach Toward a One-Pot Synthesis of 2-Arylpyrrolo[2,3,4-kl]acridin-1(2H)-ones Catalyzed by Acetic Acid Under Solvent-Free Conditions
| Autor: | Fatemeh Noori Sadeh, Mojtaba Lashkari, Nourallah Hazeri, Malek Taher Maghsoodlou |
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| Rok vydání: | 2016 |
| Předmět: |
Solvent free
010405 organic chemistry General Mathematics Isatin One-pot synthesis General Physics and Astronomy General Chemistry 010402 general chemistry 01 natural sciences Environmentally friendly 0104 chemical sciences Catalysis chemistry.chemical_compound Acetic acid chemistry Dimedone General Earth and Planetary Sciences Organic chemistry General Agricultural and Biological Sciences |
| Zdroj: | Iranian Journal of Science and Technology, Transactions A: Science. 42:1253-1258 |
| ISSN: | 2364-1819 1028-6276 |
| DOI: | 10.1007/s40995-016-0133-5 |
| Popis: | Medicinally important 2-arylpyrrolo[2,3,4-kl]acridin-1(2H)-ones are synthesized by a straightforward, efficient and convenient approach of three-component reactions of dimedone, various anilines, and isatin in the presence of acetic acid as environmentally benign and effective catalyst, under solvent-free conditions at 80 °C. This work presented here has the merits of environmental friendliness, easy operation, simple work-up, excellent yields, and inexpensive catalyst. |
| Databáze: | OpenAIRE |
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