Tödlicher Zwischenfall nach intravenöser Injektion von synthetischem ACTH

Autor: W. M. Teller, H. L. Fehm, J. Homoki, M. Müller
Rok vydání: 2008
Předmět:
Zdroj: DMW - Deutsche Medizinische Wochenschrift. 107:1353-1356
ISSN: 1439-4413
0012-0472
Popis: Synthetic 1-24adrenocorticotrophin (tetracosactid, Synacthen) is used in clinical medicine for diagnostic and therapeutic purposes. Side effects may occur due to unphysiological stimulation of endogenous adrenocortical hormone production. Allergic reactions to tetracosactid are rare. Anaphylactic shock leading to death was observed after intravenous injection of tetracosactid in a 14-year-old girl with bronchial asthma. Adrenocorticotrophin antibodies could be demonstrated after death in serum and ascitic fluid using the double antibody method.
Databáze: OpenAIRE