Tödlicher Zwischenfall nach intravenöser Injektion von synthetischem ACTH

Autor:	W. M. Teller, H. L. Fehm, J. Homoki, M. Müller
Rok vydání:	2008
Předmět:	Ascitic fluid medicine.medical_specialty Adrenocortical hormone biology business.industry Stimulation Endogeny General Medicine medicine.disease Gastroenterology Internal medicine Double antibody biology.protein medicine Antibody Complication business Asthma
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 107:1353-1356
ISSN:	1439-4413 0012-0472
DOI:	10.1055/s-2008-1070129
Popis:	Synthetic 1-24adrenocorticotrophin (tetracosactid, Synacthen) is used in clinical medicine for diagnostic and therapeutic purposes. Side effects may occur due to unphysiological stimulation of endogenous adrenocortical hormone production. Allergic reactions to tetracosactid are rare. Anaphylactic shock leading to death was observed after intravenous injection of tetracosactid in a 14-year-old girl with bronchial asthma. Adrenocorticotrophin antibodies could be demonstrated after death in serum and ascitic fluid using the double antibody method.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8c86d6bd530382ddea54e3ef6199f158 https://doi.org/10.1055/s-2008-1070129 Zobrazit plný text záznamu