Electrospinning and mechanical properties of polymeric fibers using a novel gap-spinning collector
| Autor: | Alexandros Repanas, Irene Alfred, Birgit Glasmacher, Holger Zernetsch, T. Rittinghaus, Marc Mueller |
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| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers and Plastics Scanning electron microscope General Chemical Engineering Nanotechnology 02 engineering and technology General Chemistry Polymer 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Electrospinning 0104 chemical sciences chemistry.chemical_compound Brittleness chemistry Tissue engineering Polycaprolactone Fiber Composite material 0210 nano-technology Spinning |
| Zdroj: | Fibers and Polymers. 17:1025-1032 |
| ISSN: | 1875-0052 1229-9197 |
| Popis: | Tissue engineering is an interdisciplinary field which combines the basic principles of life sciences and engineering. One promising idea is the combination of scaffolds and living cells in order to produce new functional tissue. The scaffolds play the role of a microenvironment that guides the cells towards tissue formation and regeneration. One of the most frequently used techniques to produce scaffolds is electrospinning. Tissue engineered constructs have to exhibit physiological and mechanical properties comparable to the native tissue they are intended to replace. To create polymeric fibers with controlled orientation, a cylindrical collector that rotates at a certain speed could be used, creating fibers that run longitudinally. The process of gap-spinning enables the production of specifically aligned fibers. Aim of this study was to develop a novel setup capable of producing multilayered structures with controlled fiber angle. The structural, morphological and mechanical characteristics of the fibers were accessed using scanning electron microscopy and uniaxial tensile tests. Longer pre-stretching led to thinner (in the sub-micron scale), more brittle and less elastic fibers. In a nutshell, the results indicated that fiber mats of desired orientation, fiber diameter and mechanical properties could be produced by controlled gap-spinning with a translational collector. |
| Databáze: | OpenAIRE |
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