Silver-Catalyzed Synthesis of Nitriles from Carboxylic Acids and Cyanamides
| Autor: | Jing Zhang, Mingsheng Li, Lingjian Zi, Xinqaing Chen |
|---|---|
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Synlett. |
| ISSN: | 1437-2096 0936-5214 |
| Popis: | A concise and practical silver-catalyzed nitrogen-atom-transfer protocol was developed to access versatile nitriles from ubiquitous carboxylic acids with N-cyano-N-phenyl-p-toluenesulfonamide. This protocol complements the established carboxylic acids-to-nitriles conversion methods, which suffer from laborious steps, high temperatures (≥200 °C), or limited substrate scopes. This approach operates broadly across diverse aryl, alkenyl, and primary-, secondary-, or tertiary-alkyl carboxylic acids. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|