ChemInform Abstract: Efficient Synthesis of New 5-Substituted Uracil Nucleosides Useful for Linker Arm Incorporation

Autor:	Shizen Sekiguchi, Akiko Nakamura, Masakazu Endoh, Hiroaki Sawai, Hiroaki Ozaki, Keisuke Yumoto
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Addition reaction chemistry Reaction sequence Nucleic acid Uracil General Medicine Combinatorial chemistry Linker
Zdroj:	ChemInform. 26
ISSN:	0931-7597
DOI:	10.1002/chin.199508265
Popis:	5-Substituted uracil nucleosides useful for the attachment of linker arms to nucleic acids are prepared from arabinoaminooxazoline and dimethyl α-bromomethylfumarate in a short reaction sequence without using any protecting groups, and incorporated into oligodeoxyribonucleotides.
Databáze:	OpenAIRE
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