PROLIFERATION KINETICS OF AN EXPERIMENTAL ASCITES TUMOUR OF THE MOUSE

Autor:	E. Frindel, Maurice Tubiana, A. J. Valleron, F. Vassort
Rok vydání:	1969
Předmět:	medicine.medical_treatment Cell Intraperitoneal injection Cell Biology General Medicine Cell cycle Biology Molecular biology chemistry.chemical_compound medicine.anatomical_structure chemistry Biochemistry Ascites medicine Proliferation kinetics medicine.symptom DNA
Zdroj:	Cell Proliferation. 2:51-65
ISSN:	1365-2184 0960-7722
Popis:	The cell cycles of an experimental ascitic tumour of the C3H mouse (NCTC 2472) were determined at various times after the intraperitoneal injection of 106 cells. It was found that, contrary to results in solid NCTC 2472 tumours, obtained with the same NCTC cells, the duration of the cell cycle and its phases lengthened with the age of the tumour while the growth fraction remained relatively constant. G1 was the first phase to lengthen, while later Ts and TG2 increased also. The amount of DNA per cell was determined by cytospectrophotometry. This method provides data on the evolution during growth of the relative number of cells in each phase of the cell cycle.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8c6f0ee8ff98c55841f69ddf113f2ad3 https://doi.org/10.1111/j.1365-2184.1969.tb00337.x Zobrazit plný text záznamu