Capillary Electrophoresis-Fluorescence Line-Narrowing (CE-FLN) System for DNA Adduct Characterization

Autor: Daniel S. Zamzow, Ryszard Jankowiak, Gerald J. Small
Rok vydání: 1996
Předmět:
Zdroj: Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals. 291:155-162
ISSN: 1058-725X
DOI: 10.1080/10587259608042743
Popis: Capillary electrophoresis (CE) interfaced with low-temperature (4.2 K) fluorescence line-narrowing (FLN) spectroscopy is used for separation and structural characterization of polycyclic aromatic hydrocarbon-derived DNA adducts. The CE-FLN system is applied to the separation and identification of mixtures of benzo[a]pyrene and dibenzo[a,l]pyrene DNA adducts. Interfacing CE with FLN spectroscopy allows on-line separation and high-resolution spectroscopic identification of CE-separated DNA adducts, providing a new powerful tool for DNA adduct structure characterization.
Databáze: OpenAIRE