Timing of cholecystectomy for acute cholecystitis impacts surgical morbidity and mortality: an NSQIP database analysis
| Autor: | Walid Faraj, Mohammad Khalife, Mohammad N. Hosni, Hani Tamim, Fady Daniel, Maher Malaeb, Aurelie Mailhac, Faek R. Jamali |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry Mortality rate Database analysis medicine.medical_treatment Confounding Subgroup analysis Surgery Surgical morbidity 03 medical and health sciences 0302 clinical medicine Primary outcome 030220 oncology & carcinogenesis Acute cholecystitis Medicine 030211 gastroenterology & hepatology Cholecystectomy business |
| Zdroj: | Updates in Surgery. 73:273-280 |
| ISSN: | 2038-3312 2038-131X |
| Popis: | The aim of this study is to identify the optimal timing for cholecystectomy for acute cholecystitis. Patients undergoing cholecystectomy for acute cholecystitis from the National Surgery Quality Improvement Program database between 2014 and 2016 were included. The patients were divided into 4 groups, those who underwent surgery at days 0, 1, 2, or 3+ days. The primary outcome was short-term surgical morbidity and mortality. A total of 21,392 patients were included. After adjusting for confounders, compared to day 0 patients, those who underwent surgery at day 1 and day 2 had lower composite morbidity rate, while day 3+ patients had significantly higher bleeding and mortality rate. Subgroup analysis shows this trend to be more significant in the elderly and in diabetic patients who were delayed. Delay in cholecystectomy for over 72 h from admission is associated with statistically significant increase in bleeding and mortality. |
| Databáze: | OpenAIRE |
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