Diagnosis and treatment of Helicobacter : a 2002 updated review
| Autor: | F. Perna, Christelle Basset, John Holton, Luigi Gatta, M. Miglioli, A. Tampieri, Dino Vaira, Claudio Ricci |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Hepatology biology business.industry Gastroenterology MEDLINE Rapid urease test Effective management macromolecular substances Helicobacter pylori biology.organism_classification Surgery Test (assessment) Serology medicine Pharmacology (medical) In patient Helicobacter Intensive care medicine business |
| Zdroj: | Alimentary Pharmacology & Therapeutics. 17:89-97 |
| ISSN: | 0269-2813 |
| DOI: | 10.1046/j.1365-2036.17.s2.6.x |
| Popis: | The year 2002 saw advances on many fronts in the study of Helicobacter and gastroduodenal disease. Several studies have confirmed endoscopy as a valuable management procedure with confirmation of the diagnostic utility of the rapid urease test and the description of a new formulation of the test, which is more rapid in giving a result. Serology has been re-confirmed as a useful investigation in selected populations. Some commercial kits for near patient testing have also been assessed and although generally regarded as less accurate than laboratory based tests some have shown acceptable accuracy. The recent exciting development in diagnostic serology is the availability of the faecal antigen test; further studies have confirmed its usefulness as recommended screening tests. There have been several studies demonstrating that a test and treat policy has a significant patient benefit, both economic and medical, although there is some doubt if eradication of Helicobacter leads to regression of atrophy and metaplasia. However, in low Helicobacter-prevalence areas the test and treat policy is being challenged as an effective management strategy. Further studies have shown that compliance with treatment regimens is an important determinant of successful eradication. Finally several new eradication regimens have been reported particularly for use in patients who have had previous unsuccessful eradication attempts. |
| Databáze: | OpenAIRE |
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