| Popis: |
The seed extract of the fluted pumpkin, Telfairia occidentalis (Hook, F.), agglutinates erythrocytes and is mitogenic for murine T-lymphocytes. An abundant galactose-binding lectin, T. occidentalis agglutinin, was purified from the seeds. The lectin is an N -glycosylated hexamer with three pairs of disulphide-bonded subunits and a M r of 180000. Human and porcine lymphocytes are stimulated by T. occidentalis agglutinin and this is the first known example of a mitogenic lectin from the Cucurbitaceae. Asialoproteins containing biantennary or triantennary N -glycan chains, and plant galactomannans are bound by T. occidentalis agglutinin. |
