Autor: |
Sunil Jain, Amna Qasim, Snigdha Bhatia, Maria Franco Fuenmayor, Mohammad Mehdi |
Rok vydání: |
2023 |
DOI: |
10.21203/rs.3.rs-2839000/v1 |
Popis: |
Objective Deficiencies of citrulline and arginine have been associated with adverse outcomes in preterm-infants (PI) and data regarding enteral supplementation in PI is unknown. Study Design: This randomized-controlled-trial [NCT03649932] included 42 PI (gestational age ≤ 33 weeks) randomized to receive enteral L-citrulline in low (100 mg/kg/day), medium (200 mg/kg/day) and high-dose (300 mg/kg/day) groups for 7 days. Plasma citrulline and arginine levels were obtained pre-and-post supplementation and efficacy was determined by a significant increase in levels after supplementation. A p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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