Autoimmune Diseases of the Biliary Tract
| Autor: | Sean Ronnekleiv-Kelly, Christina W. Lee |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
biology business.industry Hepatobiliary disease Hepatobiliary Disorder medicine.disease Gastroenterology Pathophysiology Primary sclerosing cholangitis Natural history 03 medical and health sciences 0302 clinical medicine Primary biliary cirrhosis Biliary tract 030220 oncology & carcinogenesis Internal medicine medicine biology.protein 030211 gastroenterology & hepatology Surgery Antibody business |
| Zdroj: | Surgical Clinics of North America. 99:185-201 |
| ISSN: | 0039-6109 |
| DOI: | 10.1016/j.suc.2018.11.003 |
| Popis: | The management of autoimmune hepatobiliary disorders remains a challenging and emerging area of investigation. An awareness of cholestatic liver diseases is critical to appropriate recognition and management of these challenging diseases, because patients often present asymptomatically, and diagnosis is limited by the lack of disease-specific markers and diagnostic studies. Furthermore, there is a paucity of treatment options because the pathophysiology underlying autoimmune biliary diseases remains largely unknown. This article discusses the natural history, clinical presentation, diagnosis, and medical and surgical management strategies for three dominant autoimmune biliary diseases: primary biliary cirrhosis, primary sclerosing cholangitis, and immunoglobulin G4-related hepatobiliary disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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