Waste-Minimized Protocol for the Synthesis of Sulfonylated N-Heteroaromatics in Water
| Autor: | Jia-Xi Tan, Long-Yong Xie, Xianyong Yu, Ning-Ning Dai, Weimin He, Rong-Xia Sun, Zilong Tang, Sha Peng, Xinhua Xu |
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| Rok vydání: | 2018 |
| Předmět: |
Reaction conditions
010405 organic chemistry Renewable Energy Sustainability and the Environment General Chemical Engineering Regioselectivity Alcohol General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound chemistry Metal free Reagent Environmental Chemistry Chemoselectivity |
| Zdroj: | ACS Sustainable Chemistry & Engineering. 6:16976-16981 |
| ISSN: | 2168-0485 |
| DOI: | 10.1021/acssuschemeng.8b04339 |
| Popis: | An ecofriendly and practical method for the efficient synthesis of various sulfonylated N-heteroaromatics in water under metal-free, organic-solvent-free, neutral, and mild reaction conditions was developed. The employment of readily available reagents, wide substrate scope, high chemoselectivity, and regioselectivity make this protocol very practical. Importantly, the pure products can be easily obtained via filtration and washing by alcohol without extraction and recrystallization. |
| Databáze: | OpenAIRE |
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