Hypoglycemic effects of Aloe vera peel extract on type 2 diabetic rats

Autor: L. B. Suromo, Wulan Christijanti, A. Z. Juniarto
Rok vydání: 2019
Předmět:
Zdroj: Journal of Physics: Conference Series. 1321:032032
ISSN: 1742-6596
1742-6588
DOI: 10.1088/1742-6596/1321/3/032032
Popis: Aloe vera is one of many medicinal plants used as hypoglycemic. Higher glucose levels are one of the characteristics of diabetes mellitus. This research aimed to study effectiveness of Aloe vera peel extract on insulin and serum glucose levels of rats with type 2 diabetic. Twenty Wistar rats were induced intraperitoneally using single dose of 65 mg/kg of streptozotocin (STZ) and 230 mg/kg of nicotinamide acid (NA). The rats were divided into control and treatment groups, which was supplemented using 100 mg/kg, 200 mg/kg and 400 mg/kg body weight of Aloe vera peel extracts for 28 days, respectively. The serum glucose levels were measured after three days of induction, 2 and 4 weeks after treatment, while the insulin levels were measured after three days of induction and at the end of treatment. In the control groups, the serum glucose levels in the second and fourth weeks remained significantly higher (p
Databáze: OpenAIRE