| Autor: |
M. A. Kaplan, V. V. Drozhzhina, J. S. Osipchuk, L. M. Arkhipova, G.V. Ponomarev, A. A. Mikhailovskaya, A. I. Malygina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Russian Journal of Biotherapy. 14:55-62 |
| ISSN: |
1726-9784 |
| Popis: |
Effectiveness of a new photosensitizer (PS) liposomal amidoaminchlorine for PDT was studied on a tumor model of rat sarcoma М-1. The research objective: to define parameters of PS minimum effective dose and laser irradiation to achieve complete regression of the tumor. Dynamics of PS accumulation in tumor and healthy tissue was studied to define the PDT time course and antitumor efficiency of different PS doses and various parameters of laser irradiation. The study results defined the optimum term for PDT and minimally effective PS dose and established the parameters for laser irradiation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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