A Multisensory Stripping Voltammetry Method for Analysis of the Generic Anti-Glaucoma Drug Betoptic

Autor:	Vladimir A. Namiot, N. A. Bakunina, I. I. Kolesnichenko, S. N. Udaltsov, Yu. D. Kuznetsova, A. N. Doronin, L. M. Balashova
Rok vydání:	2019
Předmět:	0301 basic medicine Chromatography 030102 biochemistry & molecular biology Chemistry Biophysics Glaucoma Electrochemistry medicine.disease Stripping (fiber) 03 medical and health sciences 030104 developmental biology Lacrimal fluid Interdigitated electrode medicine Voltammetry
Zdroj:	Biophysics. 64:885-889
ISSN:	1555-6654 0006-3509
Popis:	A new electrochemical method for multisensory stripping voltammetry has been used to determine whether it is appropriate for determination of generic forms of the drug Betoptic, that is, Xonef, Betoftan, and Betalink EU in tear fluid. Measurements were carried out on a planar three-electrode interdigitated electrode. It has been shown that this method is effective for determination of the generics. The dynamics of changes in their concentrations over time were examined. After instillation of the generics in glaucoma patients, their concentrations in the lacrimal fluid remained unchanged within 12 h. The list of organic substances that can be determined by the method of multisensory stripping voltammetry has been extended.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8b9c8b029171b416b4d5e86b979618ef https://doi.org/10.1134/s0006350919060046 Zobrazit plný text záznamu Full text from SpringerLink