Changes in anticholinesterase, antioxidant activities and related bioactive compounds of carob pulp (Ceratonia siliqua L.) during ripening stages
| Autor: | Hayette Louaileche, Fairouz Saci, Lynda Gali, Mostapha Bachir Bey, Chawki Bensouici |
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| Rok vydání: | 2019 |
| Předmět: |
Antioxidant
DPPH General Chemical Engineering medicine.medical_treatment 01 natural sciences Industrial and Manufacturing Engineering chemistry.chemical_compound 0404 agricultural biotechnology food medicine Food science Safety Risk Reliability and Quality Butyrylcholinesterase chemistry.chemical_classification ABTS Chemistry 010401 analytical chemistry Ripening 04 agricultural and veterinary sciences 040401 food science Acetylcholinesterase food.food 0104 chemical sciences Ceratonia siliqua Condensed tannin Food Science |
| Zdroj: | Journal of Food Measurement and Characterization. 14:937-945 |
| ISSN: | 2193-4134 2193-4126 |
| DOI: | 10.1007/s11694-019-00344-9 |
| Popis: | In the current study, in vitro neuroprotective effect of carob (Ceratonia siliqua L.) pulp (wild and cultivated varieties) at the unripe and ripe stage was investigated through testing against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), linked to Alzheimer’s disease (AD). As neurodegenerative disorders are strongly related to oxidative damage and metal accumulation, the antioxidant activity of carob extracts was determined by DPPH, ABTS, ferric reducing power (FRP), CUPRAC and ferrous iron chelating (FIC) assays at both ripening stages. Total phenolic (TPC), total flavonoids (TFC) and total condensed tannin contents (CTC) were also assessed. At the unripe stage, the samples of both varieties exhibited an interesting inhibitory effect against AChE and BChE with a strong antioxidant activity by scavenging free radicals and by acting as reducing agents. The result showed that the concentrations of TPC, TFC, and CTC were decreased significantly (P |
| Databáze: | OpenAIRE |
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