DNA ploidy and p53 expression associated with tumor site and lymph node metastasis in colorectal cancer

Autor:	Zhong-qi Xue, Guang-wei Xu, Hong-yi Wang, Shan Jin
Rok vydání:	2000
Předmět:	Cancer Research Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Colorectal cancer Aneuploidy Lymph node metastasis medicine.disease medicine.disease_cause Flow cytometry Oncology Medicine Ploidy business Carcinogenesis P53 expression Dna ploidy
Zdroj:	Chinese Journal of Cancer Research. 12:64-66
ISSN:	1000-9604
DOI:	10.1007/bf02983197
Popis:	Objective: To study the association of DNA ploidy abnormality and p53 overexpression with the carcinogenesis of colorectal cancer. Methods: DNA ploidy and p53 expression were measured in a series of 42 colorectal adenocarcinomas by means of flow cytometry and immunohistochemical test. Results: 17 tumors (40%) were diploid and 25 (60%) aneuploid. The aneuploid tumors were significantly more common in the distal colon than in the proximal colon (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8b85827b488f614a1dc3c96f541f8d2c https://doi.org/10.1007/bf02983197 Zobrazit plný text záznamu Full text from SpringerLink