Intramolecular Hetero Diels–Alder Routes to γ-Carboline Alkaloids

Autor:	J. Hodge Markgraf, Matthew G. Jarvis, Scott A. Snyder, David A. Vosburg
Rok vydání:	2000
Předmět:	Chemistry Stereochemistry Intramolecular force Organic Chemistry Drug Discovery Diels alder Biochemistry
Zdroj:	Tetrahedron. 56:5329-5335
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(00)00468-3
Popis:	Concise and efficient routes to the carboline alkaloids isocanthine (3), isocanthin-6-one (4), 1-methylisocanthine (5), and 1-methylisocanthin-6-one (6) are reported. In each case, the key synthetic step was an intramolecular hetero Diels–Alder reaction of a 1-aza-1,3-diene with an acetylenic dienophile.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8b5fc9b82239184bfe6cdd484d248d87 https://doi.org/10.1016/s0040-4020(00)00468-3 Zobrazit plný text záznamu Full Text from ScienceDirect