Liver dysfunction as a respiratory prognostic factor in COVID-19 patients

Autor:	Ayako Kimura, Takuya Ono, Shunya Matsuo, Motonao Ishikawa, Tomoko Ogasawara, Masafumi Ono, Hideki Ohno
Rok vydání:	2021
Předmět:	Prognostic factor medicine.medical_specialty Hepatology Coronavirus disease 2019 (COVID-19) business.industry Respiratory dysfunction Gastroenterology Respiratory failure Internal medicine Intensive care Medicine In patient Respiratory system Liver dysfunction business
Zdroj:	Kanzo. 62:429-432
ISSN:	1881-3593 0451-4203
Popis:	Respiratory dysfunction is a main clinical symptom of COVID-19. Liver dysfunction is also frequently reported in patients with COVID-19 and considered to be related to a poor prognosis. However, the precise mechanisms behind these findings remain unclear. We investigated the clinical features and prognostic factors related to liver dysfunction in 26 COVID-19 pa-tients. The patients with liver dysfunction had markedly higher WBC, neutrophils, CRP, and frequency of oxygen administration and markedly lower PaO2/FIO2 ratios. The patients with liver dysfunction had longer mean hospital stays. In conclusion, liver dysfunction at hospital admission may be an important prognostic factor for respiratory failure in patients with COVID-19. We must administer intensive care to these patients earlier to inhibit severe disease progression.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8b49b3494eca8ce3794fea73d0bc6b1f https://doi.org/10.2957/kanzo.62.429 Zobrazit plný text záznamu