Effect of native venom of red cobra (Naja pallida) on morphological and rheological properties of erythrocytes
| Autor: | A. V. Savushkin, E. B. Petukhov, D. B. Vasil'ev, N. N. Kvitko, N. P. Aleksandrova |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Chromatography
biology Echinocyte Cobra Venom General Medicine biology.organism_classification medicine.disease complex mixtures Molecular biology General Biochemistry Genetics and Molecular Biology Hemolysis Millipore Filters medicine Human erythrocytes computer Naja pallida computer.programming_language Cobra venom |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 120:1055-1057 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf02444984 |
| Popis: | The effect of native venom of red (spitting) cobra (Naja pallida) on human erythrocytes is studied using the methods of electron microscopy and filtration through Millipore filters. Morphological analysis reveals marked transformation of discoid erythrocytes to echinocytes. More prolonged contact of the blood with the venom impairs the deformability of erythrocytes and induces hemolysis and the sludge syndrome. The results indicate a potent cytotoxic effect of native venom of red cobra. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink