Novel Biocompatible Hydrogels via Click Chemistry

Autor: C. V. S. Brahmmananda Rao, Akella Sivaramakrishna, Gregory S. Smith, Ivaturi Sai Vighnesh, Kishor Padala, T. Boominathan, Varun Kaushal, A. S. Vijai Anand, Rakesh R. Panicker, Manne Madhava Reddy, Rajagopal Desikan, Arinjoy Das, Kari Vijayakrishna, Nandini Jain
Rok vydání: 2021
Předmět:
Zdroj: Gels Horizons: From Science to Smart Materials ISBN: 9789811571374
Popis: Currently, the designing and development of advanced hydrogel platforms is one of the important research areas due to their applications in the fabrication of functionalized materials useful in biomedical sciences. The rich literature reveals that most of these advanced materials are derived from the utilization of click reaction-based approaches through arranging the appropriate building blocks together in order to fabricate the desirable hydrogel architectures useful mainly in tissue engineering and drug delivery including the stem cell differentiation. Among the limitations of these materials, the non-degradability of synthetic polymers is responsible for the restricted usage in biomedical fields. Therefore, there is a constant demand to develop systematic methodologies for the synthesis of novel hydrogel materials to improve the degradability of the hydrogels by fine-tuning the functional groups and by incorporating more hydrophilicity for the ready hydrolysis.
Databáze: OpenAIRE