Correlation of Blashv And Blatem Genes in Extended-Spectrum Beta-Lactamase (Esbl) - Producing Acinetobacter Baumannii With Patient’s Outcome at Dr. Wahidin Sudirohusodo Hospital, Makassar
| Autor: | Nursin Abd Kadir, Tenri Esa, Rahmawati |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
biology business.industry medicine.medical_treatment Public Health Environmental and Occupational Health Esbl production biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Acinetobacter baumannii High morbidity Internal medicine polycyclic compounds medicine Beta-lactamase bacteria Statistical analysis business Gene |
| Zdroj: | Indian Journal of Public Health Research & Development. |
| ISSN: | 0976-5506 0976-0245 |
| Popis: | Acinetobacter baumannii causes the high morbidity and mortality. Acinetobacter baumannii has ESBL enzyme that makes it resistant to the mostly beta-lactam antibiotics. Some ESBL – coding genes are blaSHV and blaTEM. The purpose of this study was to evaluate correlation blaSHV and blaTEM genes in Extended Spectrum Beta-Lactamase (ESBL) - producing Acinetobacter baumannii with outcome (length of stay and death) at Dr. Wahidin Sudirohusodo Hospital, Makassar. The study used cross-sectional method conducted on Acinetobacter baumannii isolates and medical record at Dr. Wahidin Sudirohusodo, Makassar. ESBL was detected with automated culture, blaSHV and blaTEM genes was detected with PCR. Statistical analysis used Chi Square, Fisher Exact, Independent-t and Pearson’s Correlation tests. Significance of test if p0.05). It was concluded that blaTEM gene was found 93% and blaSHV was not found. The LOS in positive ESBL was significantly longer. |
| Databáze: | OpenAIRE |
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