Synthesis of new cores and their use in the preparation of polyester dendrimers

Autor:	T. Bruce Grindley, Jean-d’Amour K. Twibanire, Hussein Al-Mughaid
Rok vydání:	2010
Předmět:	Ozonolysis Organic Chemistry Biochemistry Chemical synthesis Acetic anhydride chemistry.chemical_compound End-group Propanoic acid chemistry Hydrogenolysis Dendrimer Drug Discovery Organic chemistry Hydroxymethyl
Zdroj:	Tetrahedron. 66:9602-9609
ISSN:	0040-4020
Popis:	Six dendrimer and dendron cores terminated by hydroxyl groups that are neither phenolic nor cleavable by hydrogenolysis have been prepared in a consistent one-pot manner from terminal allyl groups by reduction of the product of reductive ozonolysis. Some of the terminal allyl derivatives are new and others have been prepared by new methods. The well-known O-benzylidene derivative of 2,2′-bis(hydroxymethyl)propanoic acid was shown to be the cis-stereoisomer. A new AB3-type anhydride, tris(benzyloxymethyl)acetic anhydride has been prepared. It was demonstrated that these cores and dendrons could be assembled into first and second generation homo- and mixed polyester dendrimers.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8b2fbaf762116c085eed0540541df15e https://doi.org/10.1016/j.tet.2010.10.018 Zobrazit plný text záznamu Full Text from ScienceDirect