Carbohydrate-Based Tolylsulfonyl Hydrazines: Effective Catalysts for Michael Addition of Indoles to Electron-Deficient Olefins in Water

Autor: Peng Wu, Jiwen Cai, Yiqian Wan
Rok vydání: 2008
Předmět:
Zdroj: Synlett. 2008:1193-1198
ISSN: 1437-2096
0936-5214
DOI: 10.1055/s-2008-1072735
Popis: Carbohydrate-based tolylsulfonyl hydrazines were used for the first time to catalyze the Michael reaction of indoles to electron-deficient olefins in aqueous media to afford 3-substituted indole derivatives in good to excellent yields at room temperature.
Databáze: OpenAIRE