RABBIT PREGNANCIES AFTER IMMUNIZATION WITH EXTRACT OF THYROID GLAND1
| Autor: | William H. Beierwaltes, Robert W. Schmidt, Edward A. Carr, Vernon N. Dodson |
|---|---|
| Rok vydání: | 1961 |
| Předmět: |
endocrine system
medicine.medical_specialty Fetus endocrine system diseases biology business.industry animal diseases Thyroid Antibody titer Transplacental medicine.disease Anti-thyroid autoantibodies Thyroiditis Congenital hypothyroidism Endocrinology medicine.anatomical_structure Internal medicine medicine biology.protein Antibody business |
| Zdroj: | Endocrinology. 69:863-867 |
| ISSN: | 1945-7170 0013-7227 |
| DOI: | 10.1210/endo-69-4-863 |
| Popis: | A rough correlation was observed in mother rabbits immunized to an extract of rabbit thyroid, between the height of antithyroid antibody titer achieved and the incidence and degree of histologic changes of “thyroiditis.” No significant abnormality was observed in the thyroids of mother rabbits given saline or immunizing injections to hog or human thyroid gland. Although transplacental transfer of thyroid antibody was demonstrated and there was a high incidence of fetal death in rabbit-thyroid immunized rabbits, no evidence of congenital hypothyroidism was demonstrable in the fetuses. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|