Iron(III) complexation behavior of benzene-centered tripodal mono-, di- and tritopic ligands carrying a repeating –Ahe–(HO)Apr– sequence [Ahe = 6-aminohexanoyl; (HO)Apr = 3-(N-hydroxy)aminopropanoyl]

Autor:	Masayasu Akiyama, Akira Tsubouchi, Yukihiro Hara, Langtao Shen
Rok vydání:	2001
Předmět:	Chemistry Stereochemistry Kinetics Sequence (biology) General Chemistry Medicinal chemistry Catalysis chemistry.chemical_compound Octahedron Intramolecular force Materials Chemistry Iron removal Molecule FERRIC IRON Benzene
Zdroj:	New Journal of Chemistry. 25:275-282
ISSN:	1369-9261 1144-0546
Popis:	To investigate how three-directional molecules behave upon complexation with ferric iron, tripodal 1,3,5-benzene-centered mono-, di- and tritopic iron-chelating ligands {C6H3[CO–(Ahe–(HO)Apr)n–OH]3: 1, n = 1; 2, n = 2; 3, n = 3}, composed of strands containing an –Ahe–(HO)Apr– sequence [Ahe = 6-aminohexanoyl; (HO)Apr = 3-(N-hydroxy)aminopropanoyl], were synthesized. These hydroxamate ligands form intramolecular six-coordinate octahedral complexes with Fe(III): Fe1-1, Fe1-2, Fe2-2, Fe1-3, Fe2-3 and Fe3-3. The complexes formed were investigated from a topological viewpoint and examined in terms of stability against attack by H+ and HO−, monoprotonation equilibrium and iron removal kinetics using a 20-molar excess of EDTA. Fe1-1, Fe1-2 and Fe2-2 have tripodal interstrand structures. In particular, the iron removal reaction of Fe2-2 shows a consecutive first-order reaction pattern. From kinetic data of the first-order reactions, Fe1-3, Fe2-3 and Fe3-3 are concluded to possess one, two and three discrete ferrioxamine-type (intrastrand) structures, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8b16af780924da256011725186eda936 https://doi.org/10.1039/b005788f Zobrazit plný text záznamu