Study of Serum Magnesium level and Atherosclerotic Changes in Patient on Maintenance Hemodialysis
| Autor: | Mai Magdy Saad Zeid, Heba El Sayed Kasem Mohamed, Ahmed Rabie Alarbagy, Yassein Salah Yassein Mohamed |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Cholesterol business.industry Magnesium 030232 urology & nephrology chemistry.chemical_element 030204 cardiovascular system & hematology Logistic regression Gastroenterology Confidence interval End stage renal disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Intima-media thickness Internal medicine cardiovascular system medicine cardiovascular diseases Prospective cohort study business Lipid profile |
| Zdroj: | The Egyptian Journal of Hospital Medicine. 81:1767-1774 |
| ISSN: | 2090-7125 |
| DOI: | 10.21608/ejhm.2020.120008 |
| Popis: | Background: Cardiovascular complications in dialysis patients focused on atherosclerosis. Serum magnesium has a role in cardiovascular complications in dialysis patients. Objectives: This study aimed to study the correlation between serum magnesium level and atherosclerotic changes in patients on maintenance hemodialysis. Patients and methods: This prospective study included 60 patients with end-stage renal disease patients on maintenance HD, divided into Group I: (20 patients) with normal serum magnesium level (1.7 -2.8 mg/dl), Group II (20 patients) with low serum magnesium level ( 2.8mg/dl.). Serum magnesium and lipid profile and intima-media thickness (IMT) of both common carotid arteries were measured. Results: Our results showed a significant negative association between level of serum Mg and IMT complex of both common carotid (P = 0.045) and ischemic heart disease in the studied patients (P = 0.012). The binary logistic regression for the predictors for IHD and CCA-IMT, we found that serum magnesium not an independent factor for atherosclerosis but we found that age and DM (P ˂ 0.001) followed by cholesterol and triglycerides (P ˂ 0.05) are the most independent factors for CCA-IMT. Also, age (with OR: 95% confidence Interval) (0.145:1.26-1.06) (P ˂ 0.001) and triglycerides (1.02:1.05-1.002), (P ˂ 0.05) are the independent factors for IHD. Conclusion: Our study revealed a significant inverse correlation between level of serum Mg and CCA-IMT and IHD in the studied HD patients. Thus, we suggest that regular screening of HD patients for serum Mg and CIMT with special consideration to diabetic and old patients is recommended to stratify their CV risk. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|