Current Concepts of Neurocytoprotective Therapy

Autor:	Afanas'ev Vv, Rumiantseva Sa, O A Gomazkov, Ekaterina Vladimirovna Silina, O A Sokhova, Stupin Va
Rok vydání:	2013
Předmět:	Drug business.industry General Neuroscience media_common.quotation_subject Cognition Drug action Disease medicine.disease Bioinformatics Brain ischemia Clinical trial chemistry.chemical_compound chemistry Cerebrolysin medicine In patient business media_common
Zdroj:	Neuroscience and Behavioral Physiology. 43:374-379
ISSN:	1573-899X 0097-0549
DOI:	10.1007/s11055-013-9743-y
Popis:	The review is devoted to pharmacological effects and clinical effectiveness of one of the "oldest" neurocytoprotective drugs cerebrolysin. Experimental data that have revealed molecular mechanisms of the drug action as well as the results of clinical trials demonstrating the efficacy of cerebrolysin in the treatment of acute and chronic brain ischemia, Alzheimer's disease, moderate and mild cognitive disorders are described in details. It has been concluded that the efficacy o this drug has been supported by fundamental research, using animal models and cell cultures, and multiple clinical trials in patients with different pathologies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8b0d50074b1a9743d0231d4aa6071c32 https://doi.org/10.1007/s11055-013-9743-y Zobrazit plný text záznamu Full text from SpringerLink