Evaluation of the local vasodilator effect of acetyl-beta-methylcholine chloride (mecholyl) by iontophoresis

Autor: Sidney M. Fierst, Kamillo Flachs, David I. Abramson
Rok vydání: 1942
Předmět:
Zdroj: American Heart Journal. 23:817-822
ISSN: 0002-8703
DOI: 10.1016/s0002-8703(42)90683-5
Popis: 1. 1. The vasodilating action of mecholyl by iontophoresis was studied in the forearm, leg, and foot of nine normal subjects by means of the venous occlusion plethysmographic method. 2. 2. It was found that this procedure immediately produced a significant increase in the rate of blood flow in the forearm and foot, which continued for some time after the treatment was terminated. The effect upon the leg was less marked. 3. 3. The increase in flow was considered to be primarily the result of vasodilatation of cutaneous blood vessels, those in the muscles probably contributing little if at all to the effect.
Databáze: OpenAIRE