COVID-19 as a new risk factor for the development of acute vascular diseases of the optic nerve and retina
| Autor: | Vladimir A. Antonov, Vadim A. Turgel, Niurguyana N. Grigorieva, Fedor E. Shadrichev, Svetlana Nikolaevna Tultseva |
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| Rok vydání: | 2021 |
| Předmět: |
Retina
Pathology medicine.medical_specialty Resuscitation business.industry Context (language use) Ischemic optic neuropathy medicine.disease_cause medicine.disease medicine.anatomical_structure Optic nerve General Earth and Planetary Sciences Medicine Anterior ischemic optic neuropathy business Endotheliitis General Environmental Science Coronavirus |
| Zdroj: | Ophthalmology Reports. 14:105-115 |
| ISSN: | 2412-5423 1998-7102 |
| Popis: | The new coronavirus disease (COVID-19) is a viral respiratory infection accompanied by systemic endotheliitis. COVID-19 patients usually encounter changes related to hypercoagulability, hypofibrinolysis, and increased intravascular platelet aggregation. There is also a vascular wall thromboresistance decrease and impaired vasomotor function, which significantly increase the risk of thromboembolic complications. Currently, pathogenic aspects of the relationship between COVID-19 and vascular and inflammatory conditions of the optic nerve and retina are actively investigated. One of the triggers of impaired blood flow in ocular vessels may be a perfusion pressure decrease, observed in the acute period of the infectious process. This is related to both COVID-19 clinical course features and to resuscitation specificity as well. Secondary autoimmune inflammation is being considered as a mechanism of damage to the vascular wall in the post-infectious period. In this publication, possible pathogenic links of these diseases are considered for the first time in a specific context of the example of ischemic optic neuropathy associated with coronavirus infection. |
| Databáze: | OpenAIRE |
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