Two cases of cyclic neutropenia with acquired CSF3R mutations, with 1 developing AML

Autor:	Olga Klimenkova, Sabine Mellor-Heineke, Elisa Reinel, Karl Welte, Murat Uenalan, Cornelia Zeidler, Maksim Klimiankou, Julia Skokowa, Siarhei Kandabarau
Rok vydání:	2016
Předmět:	0301 basic medicine business.industry Immunology Cell Biology Hematology medicine.disease Biochemistry 03 medical and health sciences Cyclic neutropenia 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Medicine Congenital Neutropenia business
Zdroj:	Blood. 127:2638-2641
ISSN:	1528-0020 0006-4971
DOI:	10.1182/blood-2015-12-685784
Popis:	To the editor: Congenital neutropenia (CN) and cyclic neutropenia (CyN) are rare genetic disorders of hematopoiesis predominantly caused by ELANE mutations.[1][1][⇓][2]-[3][3] Due to overlaps in their genetic profiles, CyN can be distinguished from CN by cycling neutrophil counts, usually at 21
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8ade9168a79df173d20970685c298dec https://doi.org/10.1182/blood-2015-12-685784 Zobrazit plný text záznamu