133Xenon ventilation scintigraphy applied to bronchoscopic lung volume reduction techniques for emphysema: relevance of interlobar collaterals

Autor: Lynda Holsworth, M.J. Kelly, J Salanitri, Trevor Williams, Gregory I Snell, Victor Kalff
Rok vydání: 2005
Předmět:
Zdroj: Internal Medicine Journal. 35:97-103
ISSN: 1444-0903
DOI: 10.1111/j.1445-5994.2004.00746.x
Popis: Background: 133Xenon ventilation scintigraphy and 99mTc-MAA perfusion scintigraphy can be used to assess dynamic ventilation patterns in patients with severe emphysema. Aim: To describe the scintigraphic features of attempted bronchoscopic lung volume reduction (BLVR), exploring mechanisms that might explain the unexpected lack of postoperative atelectasis. Methods: Five patients with heterogenous severe upper lobe emphysema were evaluated with 133Xenon ventilation and 99mTc-MAA perfusion scintigraphy, chest radiography, bronchoscopy and high resolution computed tomography before and up to 1 month after endoscopic placement of bronchial prostheses (BLVR). Ex vivo assessment of the lungs of two further patients with severe upper lobe emphysema was performed. Results: No significant subsegmental or lobar collapse was evident on post-procedure chest radiography or high resolution computed tomography, despite bronchoscopic confirmation of adequate position and functioning of prostheses. 133Xenon ventilation scintigraphy confirms significantly decreased upper lobe wash-in (P
Databáze: OpenAIRE