The relationship between cellular responses of parous women and ovarian cancer patients to tumour extracts
| Autor: | Terry Poulton, C.N. Hudson, M. E. Crowther |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Oncology
endocrine system medicine.medical_specialty Pregnancy endocrine system diseases business.industry Significant difference Obstetrics and Gynecology medicine.disease female genital diseases and pregnancy complications In vitro medicine.anatomical_structure Antigen Internal medicine Ovarian carcinoma medicine business Ovarian cancer reproductive and urinary physiology Sensitization Normal female |
| Zdroj: | Journal of Obstetrics and Gynaecology. 1:263-267 |
| ISSN: | 1364-6893 0144-3615 |
| DOI: | 10.3109/01443618109067394 |
| Popis: | SummaryThe lymphocytes of patients with ovarian carcinoma have been shown to be sensitized to antigenic determinants on ovarian tumour cells or in tumour cell membrane extracts. The blastogenic assay was used to demonstrate that normal female controls, as well as patients with ovarian cancer and pregnant women, also show in vitro responses to ovarian tumour extracts. There is a significant difference between parous and nulliparous women (P < 0·007) in their ability to respond. The lower incidence of parous women with ovarian cancer may result from previous sensitization to onco-fetal antigens during pregnancy |
| Databáze: | OpenAIRE |
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