A population of CD20+CD27+CD43+CD38lo/int B1 cells in PNH are missing GPI-anchored proteins and harbor PIGA mutations
| Autor: | Isao Tawara, Hiroshi Miwa, Naoyuki Katayama, Kohshi Ohishi, Masahiro Masuya, Yuki Kageyama |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
CD20 CD43 education.field_of_study Mutation biology Immunology Population Cell Biology Hematology CD38 medicine.disease_cause Biochemistry Molecular biology Phenotype B-1 cell 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Immunoglobulin M biology.protein medicine education 030215 immunology |
| Zdroj: | Blood. 134:89-92 |
| ISSN: | 1528-0020 0006-4971 |
| Popis: | TO THE EDITOR: B1 cells were first described in 1983 as a rare B-lymphocyte subpopulation that spontaneously secreted immunoglobulin M (IgM) and appeared to be distinguished from B2 cells.[1][1] The functional properties, phenotype, and ontogeny of B1 cells differ from those of B2 cells.[2][2] In |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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