R-Hexitronic acid, a new tetronic acid derivative isolated from a soil fungus FG9RK
| Autor: | Zhen Liu, Festus B. C. Okoye, Charles O. Esimone, Kenneth G. Ngwoke, Dina H. El-Kashef, Peter Proksch, Elena Ancheeva, Georgios Daletos |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Stereochemistry Metabolite Organic Chemistry Absolute configuration Plant Science Ring (chemistry) 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Side chain Fermentation Tetronic acid Derivative (chemistry) Lactone |
| Zdroj: | Natural Product Research. 35:3578-3583 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2020.1715400 |
| Popis: | A new tetronic acid derivative (1) together with terrestric acid (2), a known metabolite of Penicillium species, was isolated from the soil fungus, FG9RK following fermentation on solid rice medium. The structure of 1 was elucidated by one- and two-dimensional NMR and MS measurements. The absolute configuration of the oxygenated carbon in the side chain of 1 was identified as S by converting the compound into its Mosher ester whereas the absolute configuration of the lactone ring was deduced based on biogenetic considerations and comparison with 2. |
| Databáze: | OpenAIRE |
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