Internal dose assessment for 211At α-emitter in isotonic solution as radiopharmaceutical
| Autor: | V. A. Drozdov, S. Yu. Platonov, D. O. Eremenko, A. V. Tultaev, O. A. Yuminov, O. V. Fotina, A.B Priselkova |
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| Rok vydání: | 2003 |
| Předmět: |
endocrine system
Nuclear and High Energy Physics medicine.medical_specialty endocrine system diseases business.industry medicine.medical_treatment Thyroid medicine.disease Radiation therapy chemistry.chemical_compound medicine.anatomical_structure chemistry Pharmacokinetics Internal dose Sodium iodide Isotonic medicine Medical physics Nuclear medicine business Instrumentation Thyroid cancer Endocrine gland |
| Zdroj: | Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 212:516-520 |
| ISSN: | 0168-583X |
| Popis: | The functional fitness of the α-emitter 211At for radiotherapy of the thyroid gland cancer is evaluated. Radiation doses are calculated using the MIRD method and previously obtained pharmacokinetic data for 211At in isotonic solution and for 123I as sodium iodide. Analysis of the 211At radiation dose to the thyroid gland suggests that this radiopharmaceutical may be predominantly used for the treatment of the thyroid cancer. |
| Databáze: | OpenAIRE |
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