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Objective To provide more scientific and authoritative theoretical basis for body-building exercises after analyzing the changes of exercises of different intensities for the kidney functions. Methods The objects of the research are eight male students from Guangzhou Sport College, being exerted the treadmill exercises according to their own maximum oxygen intake. The intensities of exercises are respectively 55%VO2max, 75%VO2max, 85%VO2max, 95%VO2max. The urine 40ml and venous blood 3ml will be collected and tested before sport and 15minutes after the exercises. Results After four different intensities of exercise, the renin of each exercise group increased compared with the quiet value, and the greater the intensity, the more obvious the trend of change. Compared with the quiet value, the expression of angiotensin II increased in all groups after exercise, but there was no significant difference between the 55%VO2max intensity group and the 75%VO2max intensity group (P > 0.05), and there was significant difference between the 85%VO2max intensity group and the 95%VO2max intensity group (P < 0.05). Compared with the quiet value, the expression of aldosterone increased after each exercise. The mean value of 55%VO2max intensity group, 75%VO2max intensity group and 85%VO2max intensity group increased, but the difference was not significant (P > 0.05), and the 95%VO2max intensity group had a very significant difference (P < 0.01). The expression of urine beta 2 microglobulin was compared with the quiet value. There was significant difference in 85%VO2max intensity group and 95%VO2max intensity group (P |