A Cross-Sectional Study in Patients with Severe COPD to Assess the Perception of Symptom Variability (COPVAR) in the Middle East and Africa
| Autor: | Amr S. Albanna, Ashraf Alzaabi, Elmas Malvolti, Richard N. van Zyl-Smit, Alev Gürgün, Noureddine Zidouni, Wael Abuharbid, Hakan Günen, Nurdan Kokturk, Mousa Khadadah, Medhat Soliman |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
COPD Exacerbation business.industry Cross-sectional study medicine.medical_treatment General Medicine Severe copd medicine.disease 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Quality of life Internal medicine Medicine Smoking cessation In patient 030212 general & internal medicine business Morning |
| Zdroj: | International Journal of Chronic Obstructive Pulmonary Disease. 14:2959-2970 |
| ISSN: | 1178-2005 |
| Popis: | Purpose This study was performed to assess symptom variability and its impact on morning activities in stable patients with severe COPD in the Middle East and Africa (MEA) countries. Patients and methods Non-interventional, cross-sectional study (NCT03425760) in patients with severe COPD (GOLD 2015, C, or D categories). Symptom variability was assessed directly by interviewing the patient and using the Global Chest Symptoms Questionnaire (GCSQ). The impact on morning activities was assessed using the Capacity of Daily Living during the Morning (CDLM) and the Morning Activities and Symptoms Questionnaire (MASQ). Results A total of 3253 patients (mean±SD age: 64.1±9.5 years, 90.3% males) were enrolled. Overall, 81.6% and 83.4% of patients reported weekly and daily symptom variability, respectively. The number of exacerbations in the previous year, smoking cessation, and COPD GOLD D were the most consistent factors associated with symptom variability. The GCSQ score was significantly higher (p |
| Databáze: | OpenAIRE |
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